Ctrl + Click to deselect an item on selectable list

Ctrl + Click to deselect an item on selectable list


You can use ctrl and a mouse click to select items that are non-
adjacent. However if you try to click a selected item while holding
control it does not deselect it.
A sample is windows explorer. Make your selection either with ctrl to
select individual items or a lasso for multiple items, or a
combination of both. After you do that you can deselect whatever you
want and keep the rest selected by holding ctrl and and click a
selected item.
Can this be mimicked in a selectable list?
Thanks,