How do i change the content of a specific div in a cell of a grid?

How do i change the content of a specific div in a cell of a grid?

Currently i am using this to modify the "html" of a specific "column/cell" by finding the "td" of the "grid" at specific "rows".
  1. $("#VGrid1_MainGrid tr:nth-child(" + iRowNumberGrid + ")").find('td').eq(26).html("HTMLHERE");
After that is done, how do I [ (a) access, (b) modify ] the individual "div" content that is in it for the "Grid" at particular "row" and "column"? RowNumber = 2, column = 26

Example
  1. <td>
  2. <div class="myclass">
          <div id="div1">yes man</div>

  3.       <div id="div2">Add content</div>

  4. </div>
    <td>

Thanks.