jqGrid Inline edit drop down slow and high CPU

jqGrid Inline edit drop down slow and high CPU

I am now having a requirement that there are over 50 columns to be implemented as an inline edit grid. Each of them is a drop down, and some drop downs containing over hundred options. Under this situation, I find that when I select row the client PC will be on high CPU and the performance will be quite slow. Is there any way to optimize?  Thank you for all help in advance.