Jquery Mobile to Build a Mobile Supported Web App

Jquery Mobile to Build a Mobile Supported Web App

We are looking to build a web app that should be easily accessible from mobile devices. The primary use will be through web browsers, however it would be great if it can be used from mobile devices / tablets as easily.

We are currently looking at Sencha Touch and JQuery Mobile. Leaning towards JQM, since Sencha Touch limits us and our customers to the WebKit universe.

The real question that we have:

   Can we start building a full fleshed web app with JQuery Mobile, or there are limitations for "desktop browser based" web apps?

Thank you.