Disable Radio Button and textbox on Form Load

Disable Radio Button and textbox on Form Load

I have a form and want to disable some fields when form loads.

So if Radio button was checked before the form was closed by a user, then disable those that Radio  button when the same user reload the form. A save button attached to the form must also be disabled.  When the user make changes by clicking on another radio button, then enable save button for submission .

Any help will be appreciated